• Eduardo R Núñez, Ito FukunagaMayukoMUniversity of Massachusetts Chan Medical School Worcester, MA., Gregg A Stevens, James K Yang, Sarah E Reid, Jennifer L Spiegel, Molly R Ingemi, and Renda Soylemez Wiener.
• University of Massachusetts Chan Medical School-Baystate, Springfield, MA. Electronic address: eduardo.nunez2@baystatehealth.org.
• Chest. 2024 Sep 1; 166 (3): 632648632-648.

Topic ImportanceLung cancer screening (LCS) has the potential to decrease mortality from lung cancer by 20%. Yet, more than a decade since LCS was established as an evidence-based practice, < 20% of the eligible population in the United States has been screened. This review focuses on critically appraising interventions that have been designed to increase the initial uptake of LCS, including how they address known barriers to LCS and their effectiveness in overcoming these barriers.Review FindingsStudies were categorized based on the primary barriers that they addressed: (1) identifying eligible patients (including enhancing awareness through smoking history collection, outreach, and education), (2) shared decision-making-related interventions, and (3) patient navigation interventions. Four of the studies included multicomponent interventions, which often included patient navigation as one of the components. Overall, the effectiveness of the studies reviewed at improving LCS uptake generally was modest and was limited by the multilevel barriers that need to be overcome. Multicomponent interventions generally were more effective at improving LCS uptake, but most studies still had relatively low completion of screening.SummaryImproving uptake of LCS requires learning from prior interventions to design multilevel interventions that address barriers to LCS at key steps and identifying which components of these interventions are effective and generalizable.Copyright © 2024 American College of Chest Physicians. All rights reserved.

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