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Randomized Controlled Trial Multicenter Study
[Results of a randomized double-blind multicenter clinical trial of the efficacy and safety of riamilovir in the treatment of COVID-19].
- A U Sabitov, D A Lioznov, K V Zhdanov, E P Tikhonova, E V Esaulenko, O P Kovtun, P L Kuznetsov, and P V Sorokin.
- Ural State Medical University.
- Terapevt Arkh. 2024 Jun 3; 96 (5): 517522517-522.
AimTo evaluate the efficacy and safety of riamilovir in the treatment of COVID-19 in adults.Materials And MethodsThe study included 180 patients with a laboratory-confirmed diagnosis of COVID-19 which fully meet the criteria for inclusion, non-inclusion and exclusion, signed a voluntary informed consent to participate in a clinical trial.ResultsThe efficacy, good tolerability and safety of the drug riamilovir in the treatment of COVID-19 have been established.ConclusionAs a result of a multicenter randomized double-blind clinical trial, the effectiveness of the drug riamilovir for therapeutic use in patients with COVID-19 according to the 1250 mg/day scheme (250 mg capsules 5 times per day) for 10 days was established. The drug riamilovir in a daily dose of 1250 mg for 10 days does not differ in safety from placebo.
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