Using the SWITCHMRK and MONET trials as examples, Andrew Carr and colleagues question the ethics and motives of switch or simplification trials of anti-retroviral therapy.
Clinical Research Program, Centre for Applied Medical Research, St Vincent's Hospital, Sydney, Australia. acarr@stvincents.com.au
PLoS Med. 2012 Jan 1; 9 (7): e1001240e1001240.
AbstractUsing the SWITCHMRK and MONET trials as examples, Andrew Carr and colleagues question the ethics and motives of switch or simplification trials of anti-retroviral therapy.