• Maria Victoria Mazzolenis, Gabrielle Naime Mourra, Sacha Moreau, Maria Emilia Mazzolenis, Ivo H Cerda, Julio Vega, James S Khan, and Alexandra Thérond.
• Favaloro University, Buenos Aires, Argentina.
• Curr Pain Headache Rep. 2024 Sep 1; 28 (9): 881892881-892.

Purpose Of ReviewThis review investigates the roles of artificial intelligence (AI) and virtual reality (VR) in enhancing cognitive pain therapy for chronic pain management. The work assesses current research, outlines benefits and limitations and examines their potential integration into existing pain management methods.Recent FindingsAdvances in VR have shown promise in chronic pain management through immersive cognitive therapy exercises, with evidence supporting VR's effectiveness in symptom reduction. AI's personalization of treatment plans and its support for mental health through AI-driven avatars are emerging trends. The integration of AI in hybrid programs indicates a future with real-time adaptive technology tailored to individual needs in chronic pain management. Incorporating AI and VR into chronic pain cognitive therapy represents a promising approach to enhance management by leveraging VR's immersive experiences and AI's personalized tactics, aiming to improve patient engagement and outcomes. Nonetheless, further empirical studies are needed to standardized methodologies, compare these technologies to traditional therapies and fully realize their clinical potential.© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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