• Hacer Doğan Varan, Olgun Deniz, Süheyla Çöteli, Rana Tuna Doğrul, Muhammet Cemal Kizilarslanoğlu, and Berna Göker.
• Division of Geriatric Medicine, Department of Internal Medical Sciences, Faculty of Medicine, Gazi University, Ankara, Turkey.
• Turk J Med Sci. 2022 Jan 1; 52 (2): 323328323-328.

Background/AimFrailty is an important, multidimensional geriatric syndrome defined as increased vulnerability to stressors. Fried frailty phenotype (FFP) is one of the most widely used models to define physical frailty. The aim of this study is to investigate the cross-cultural validity and reliability of Fried frailty phenotype (FFP) in older Turkish population.Materials And MethodsA total of 450 patients, aged 59 years and over, were included. FFP translated into Turkish was used. Hand grip strength cut-off values that best predict low skeletal muscle mass index (SMI) for Turkish men and women were calculated. A modified version of FFP was created by rescoring FFP according to these cut-off values applicable to Turkish population. Correlation analysis between the frailty assessment by comprehensive geriatric evaluation of clinician experienced in geriatric medicine, and FFP and modified version of FFP were performed for validation. Thirty-five patients underwent frailty assessment with FFP twice for reliability assessment. Inter-rater and intra-rater agreements were investigated.ResultsClinician's decision of frailty status demonstrated significant agreement with the results of FFP, as well as modified FFP. Interrater and intra-rater compliance were good. Best hand grip strength cut-off values for predicting low SMI in older Turkish population were determined as ≤13.6 kg (AUC: 0.841, p < 0.001) for women and ≤27.7 kg for men (AUC: 0.779; p < 0.001). Modified FFP had a good agreement with the FFP.ConclusionFFP is a valid and reliable tool for Turkish population.© TÜBİTAK.

4 keywords...

hide…