• The lancet oncology · Jun 2024

    Review

    Addressing challenges in low-income and middle-income countries through novel radiotherapy research opportunities.

    • May Abdel-Wahab, C Norman Coleman, Jesper Grau Eriksen, Peter Lee, Ryan Kraus, Ekaterina Harsdorf, Becky Lee, Adam Dicker, Ezra Hahn, Jai Prakash Agarwal, Pataje G S Prasanna, Michael MacManus, Paul Keall, Nina A Mayr, Barbara Alicja Jereczek-Fossa, Francesco Giammarile, In Ah Kim, Ajay Aggarwal, Grant Lewison, Jiade J Lu, Douglas Guedes de Castro, KongFeng-Ming SpringFSDepartment of Clinical Oncology, HKU-Shenzhen Hospital and Queen Mary Hospital, Li Ka Shing Faculty of Medicine, Hong Kong Special Administrative Region, China., Haidy Afifi, Hamish Sharp, Verna Vanderpuye, Tajudeen Olasinde, Fadi Atrash, Luc Goethals, and Benjamin W Corn.
    • Division of Human Health, International Atomic Energy Agency, Vienna, Austria. Electronic address: m.abdel-wahab@iaea.org.
    • Lancet Oncol. 2024 Jun 1; 25 (6): e270e280e270-e280.

    AbstractAlthough radiotherapy continues to evolve as a mainstay of the oncological armamentarium, research and innovation in radiotherapy in low-income and middle-income countries (LMICs) faces challenges. This third Series paper examines the current state of LMIC radiotherapy research and provides new data from a 2022 survey undertaken by the International Atomic Energy Agency and new data on funding. In the context of LMIC-related challenges and impediments, we explore several developments and advances-such as deep phenotyping, real-time targeting, and artificial intelligence-to flag specific opportunities with applicability and relevance for resource-constrained settings. Given the pressing nature of cancer in LMICs, we also highlight some best practices and address the broader need to develop the research workforce of the future. This Series paper thereby serves as a resource for radiation professionals.Copyright © 2024 Elsevier Ltd. All rights reserved, including those for text and data mining, AI training, and similar technologies.

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