• Medicina · Apr 2024

    Case Reports

    Rare Orbital Involvement Originating from Extranodal Marginal Zone Lymphoma.

    • Yao-Chang Wen, Tzu-Chuan Huang, Wen-Chiuan Tsai, and Shiue-Wei Lai.
    • Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei 114202, Taiwan.
    • Medicina (Kaunas). 2024 Apr 25; 60 (5).

    AbstractOcular adnexa region (OAR) primary lymphomas are uncommon, accounting for 1-2% of non-Hodgkin lymphomas and 8% of extranodal lymphomas. Extranodal marginal zone lymphoma (EMZL) originates from several epithelial tissues, including the stomach, salivary gland, lung, small intestine, thyroid gland, and ocular adnexa region. Here, we report a 66-year-old female patient who was diagnosed with EMZL of OAR. In consideration of the possible side effect of radiotherapy, such as conjunctivitis, visual acuity impairment, and even retinal complications, she received six cycles of triweekly targeted chemotherapy with rituximab, cyclophosphamide, vincristine, and prednisone (R-CVP) without radiotherapy. Then, she remained in complete remission up to the present day.

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