• Medicine · Jun 2024

    Treating refractory thin endometrium through a novel way of activation and administration of Platelet-rich plasma in sexually active women: An interventional prospective cohort clinical study.

    • Rasha Abbassi, Sultaneh Haddad, Farah Haneyah, Wael Nakawa, Mohammed Subhi Murad, Abdulmoez Mohammed Issa, Ahmad Alkheder, Adel Azar, Majd Dakhalalah Bani Hani, and Haitham Abbassi.
    • University Hospital of Obstetrics and Gynecology in Damascus, Damascus, Syrian Arab Republic.
    • Medicine (Baltimore). 2024 Jun 14; 103 (24): e38554e38554.

    AbstractA prospective cohort study investigated the effectiveness of platelet-rich plasma (PRP) infusion for refractory thin endometrium in 38 infertile patients. Patients showed significant improvement in endometrial thickness post-PRP injection, leading to successful implantation and pregnancy. The study revealed a negative correlation between antimullerian hormone (AMH) levels and the need for PRP interventions, suggesting higher ovarian reserve may reduce the necessity for repeated treatments. This implies AMH levels could serve as a prognostic indicator for treatment outcomes, aiding clinicians in optimizing protocols and reducing patient burden. Further research is needed to confirm these findings in larger and more diverse populations, along with exploring long-term reproductive success rates post-PRP treatment.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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