• Osman Sezer Çinaroğlu, Hüseyin Acar, Hakan Çamyar, Ejeder Saylav Bora, Mehet Göktuğ Efgan, Uğur Bayram Korkmaz, Güner Yurtsever, and Efe Kanter.
• Medicine Faculty, Emergency Medicine Department, İzmir Katip Çelebi University, İzmir, Turkey.
• Medicine (Baltimore). 2024 Jun 21; 103 (25): e38599e38599.

Abstractwalled-off pancreatic necrosis (WOPN) is one of the complications of acute pancreatitis (AP) with high mortality. A method to predict the development of WOPN in AP patients admitted to the emergency department may guide life-saving practices such as early initiation of antibiotic therapy and, when necessary, referral of the patient to a center where necrosectomy can be performed. This study is a prospective observational study. One hundred eleven AP patients who applied to the emergency department were included in the study. The mean of QT interval (QT) dispersion, systemic immune-inflammation Index (SII), multi-inflammatory index-I (MII-1), multi-inflammatory index-II (MII-2), and multi-inflammatory index-III (MII-3) were compared between patients who developed WOPN and patients who did not develop WOPN during their hospitalization. In the study, the mean of QT dispersion, SII, MII-1, MII-2, and MII-3 were significantly lower in the patient group who developed WOPN compared to those who did not develop WOPN. In the receiver operating characteristic analysis, all methods except SII were found to be successful in predicting WOPN. QT dispersion, SII, MII-1, MII-2, and MII-3 are valuable tools that provide rapid results and successfully predict the development of WOPN in AP. However, MII-2 and QT dispersion appears to be slightly more successful than the others.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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