• ChenMichael Jian-WenMJDepartment of Orthopedic Surgery, China Medical University Hospital, China Medical University, Taichung, Taiwan.Spine Center, China Medical University Hospital, China Medical University, Taichung, Taiwan., Yuan-Shun Lo, Chia-Yu Lin, Chun Tseng, Pang-Hsuan Hsiao, Chien-Ying Lai, Ling-Yi Li, and Hsien-Te Chen.
• Department of Orthopedic Surgery, China Medical University Hospital, China Medical University, Taichung, Taiwan.
• Eur Spine J. 2024 Sep 1; 33 (9): 336933803369-3380.

PurposeThis study aimed to consolidate the evidence regarding the prognostic influence of sarcopenia in degenerative lumbar spine surgeries.MethodsA literature search of public databases was conducted up to Nov 15, 2023 using combinations of the key words "sarcopenia" and "lumbar spine surgery". Eligible studies were those that focused on adults undergoing decompression or fusion surgery for degenerative lumbar spine diseases, and compared the outcomes between patients with and without preoperative sarcopenia. Primary outcomes were change in ODI and back and leg pain VAS pain scores. Secondary outcomes were changes in Eq. 5D, JOA, SFHS-p scores, and LOS.ResultsUltimately, nine retrospective studies with a total of 993 patients were included. Sarcopenic patients exhibited significantly worse functional improvement as assessed by ODI compared to non-sarcopenic patients (pooled standardized mean difference [pSMD] = 0.53, 95% confidence interval [CI]: 0.17-0.90). Back pain (pSMD = 0.31, 95% CI:0.15-0.47) and leg pain (pSMD = 0.21, 95% CI:0.02 - 0.39) improvement were also less in sarcopenic patients. Non-sarcopenic patients had greater improvements in Eq. 5D (pSMD = 0.25) and SFHS-p (pSMD = 0.39), and shorter LOS (pSMD = 0.62).ConclusionsAs compared to patients without sarcopenia, those with sarcopenia undergoing lumbar spine surgery for degenerative diseases have lower improvements in functional ability, quality of life, physical health, pain relief and extended hospitalization compared to those without sarcopenia.© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

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