• Annals of medicine · Dec 2024

    Exploration of the risk factor for infarction after revascularization in moyamoya disease.

    • Tao Sun, Qiuhua Zeng, Lixin Huang, Jun Sun, Zhimin Wu, Baoyu Zhang, Cong Ling, Chuan Chen, and Hui Wang.
    • Department of Neurosurgery, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China.
    • Ann. Med. 2024 Dec 1; 56 (1): 23628722362872.

    ResultsEventually, 108 consecutive patients received 174 surgeries were enrolled, experienced new or expanded infarction occured in 13 (7.47%) surgeries, which showed higher Suzuki stage on the non-operative side, more posterior cerebral artery (PCA) involvement, and more intraoperative hypotension compared to those without infarction(p < .05). The Suzuki stage on the non-operative side had the highest area under the curve (AUC) of 0.737, with a sensitivity of 0.692 and specificity of 0.783. Combination of the three factors showed better efficiency, with an AUC of 0.762, a sensitivity of 0.692, and a specificity of 0.907.ConclusionsRevascularization was a safe option for patients with MMD, higher Suzuki stage on the non-operative side, PCA involvement, and intraoperative hypotension might be the risk factors for new or expanded infarction after revascularization in patients with MMD.

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