• Medicina clinica · Aug 2024

    Cost-effectiveness and safety of mediastinal transbronchial cryobiopsy guided by endobronchial ultrasonography (CRYO-EBUS) in 110 cases.

    • Esperanza Salcedo Lobera, Francisco M Páez Codeso, and Estefania Casado Miranda.
    • Unidad de gestión clínica médico-quirúrgica de enfermedades respiratorias, Hospital Regional Universitario de Málaga, Málaga, España. Electronic address: esalcedolobera@gmail.com.
    • Med Clin (Barc). 2024 Aug 30; 163 (4): 183185183-185.

    IntroductionTransbronchial needle aspiration guided by endobronchial ultrasonography (EBUSTBNA) has the disadvantage of sometimes offering samples of an unsuitable size for an accurate histo-molecular diagnosis. Transbronchial mediastinal cryobiopsy (CRYOEBUS) is a very novel and additional technique to EBUS-TBNA that allows us to obtain larger and quality samples, improving diagnostic performance.Material And MethodsDescriptive study of 110 patients with lesions and/or mediastinal lymphadenopathy who underwent EBUS-TBNA and CRYO-EBUS in a single procedure. Our objective was to analyze the diagnostic profitability and safety of the technique.ResultsCRYO-EBUS obtained samples of 0.42cm on average compared to 0.14cm obtained by EBUS-TBNA. The overall diagnostic performance of the techniques was 60% for EBUS-TBNA and 94.5% for CRYO-EBUS. Furthermore, the latter was more sensitive for the diagnosis of both malignant and benign diseases. With a very high security profile.ConclusionsThe CRYO-EBUS technique is cost-effective and safe, and is superior to EBUS-TBNA. Future studies may confirm our findings.Copyright © 2024 Elsevier España, S.L.U. All rights reserved.

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