Pharmacotherapy for older people with obesity.

Eur. J. Intern. Med. · Dec 2024

Review

Pharmacotherapy for older people with obesity.

Rates of obesity continue to rise, including in older adults. Use of medication for obesity in the elderly has been considered controversial, due to concerns around potential progression of age-related sarcopenia and a general lack of evidence for its use in this age group. ⋯ We evaluate in detail the anti-obesity medications currently licenced in Europe, with emphasis on the available efficacy, safety and cardiovascular outcome data gathered from study of older people. Finally, we discuss future directions and avenues of research.

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- Luke D Boyle, Feray Akbas, Dilek Yazıcı, Barbara M McGowan, and Volkan Yumuk.
- Centre for Obesity, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom. Electronic address: luke.boyle3@nhs.net.
- Eur. J. Intern. Med. 2024 Dec 1; 130: 333733-37.
AbstractRates of obesity continue to rise, including in older adults. Use of medication for obesity in the elderly has been considered controversial, due to concerns around potential progression of age-related sarcopenia and a general lack of evidence for its use in this age group. Within this review, we describe the general considerations when prescribing obesity pharmacotherapy for older adults living with obesity. We evaluate in detail the anti-obesity medications currently licenced in Europe, with emphasis on the available efficacy, safety and cardiovascular outcome data gathered from study of older people. Finally, we discuss future directions and avenues of research.Copyright © 2024. Published by Elsevier B.V.

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Pharmacotherapy for older people with obesity.

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