• JoubahMohammed BinMBDepartment of Pediatrics, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia., Ahmed Abdelaziz Ismail, Gaser Abdelmohsen, Khouloud Abdulrhman Alsofyani, Ahmed Ali Yousef, Majed Tareq Jobah, Adeeb Khawaji, Mohamed Abdelmawla, Mohamed Hesham Sayed, and Ahmed Mohamed Dohain.
• Department of Pediatrics, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
• J. Cardiothorac. Vasc. Anesth. 2024 Sep 1; 38 (9): 200220082002-2008.

ObjectivesThe aims of this study were to assess the impact of the closed-loop sampling method on blood loss and the need for blood transfusion in pediatric patients following cardiac surgery.DesignRetrospective observational study.SettingA single tertiary center.ParticipantsAll pediatric patients younger than 4 years old who were admitted to the pediatric intensive care unit (PICU) after cardiac surgery were enrolled. The study included 100 pediatric patients in the conservative (postimplementation) group and 43 pediatric patients in the nonconservative group (preimplementation).InterventionsObservational.MeasurementsThe primary outcome was the volume of blood loss during the PICU follow-up period. The secondary outcomes were the requirement for blood transfusion in each group, duration of mechanical ventilation, length of intensive care unit (ICU) stay, length of hospital stay, and mortality.Main ResultsIn the conservative (postimplementation) group, blood loss during the follow-up period was 0.67 (0.33-1.16) mL/kg/d, while it was 0.95 (0.50-2.30) mL/kg/d in the nonconservative (preimplementation) group, demonstrating a significant reduction in blood loss in the conservative group (p = 0.012). The groups showed no significant differences in terms of the required blood transfusion volume postoperatively during the first 24 hours, first 48 hours, or after 48 hours (p = 0.061, 0.536, 0.442, respectively). The frequency of blood transfusion was comparable between the groups during the first 24 hours, first 48 hours, or after 48 hours postoperatively (p = 0.277, 0.639, 0.075, respectively). In addition, the groups did not show significant differences in the duration of mechanical ventilation, length of ICU stay, length of hospital stay, or mortality.ConclusionsThe closed-loop sampling method can be efficient in decreasing blood loss during postoperative PICU follow-up for pediatric patients after cardiac surgeries. However, its application did not reduce the frequency or the volume of blood transfusion in these patients.Copyright © 2024 Elsevier Inc. All rights reserved.

31 keywords...

hide…