• Southern medical journal · Mar 1996

    Intrathecal infusion systems for treatment of chronic low back and leg pain of noncancer origin.

    • U Tutak and D M Doleys.
    • Department of Anesthesiology and Pain Management Services, HealthSouth Medical Center, Birmingham, Ala, USA.
    • South. Med. J. 1996 Mar 1;89(3):295-300.

    AbstractIn this study, 26 patients (average age, 44.3 years) with chronic noncancer pain averaging 115 months' duration had implantation of an infusion pump with intrathecal catheter placement. In general, preservative-free morphine sulfate was used. Average follow-up was 23 months. Measurements of pain reduction, activity improvement, oral medication use, and overall satisfaction by patient, spouse, and clinic staff were obtained. Of the 26 patients, 20 noted a good or excellent outcome. Average daily dosage of intrathecal morphine increased over time by approximately sevenfold. Subjective pain levels decreased an average of 59%, and daily functioning increased 50%. No postoperative complications were noted, but 11 patients required additional surgery (9 for catheter complications). These data support chronic spinal opiate therapy as an option for safe and long-term management of noncancer pain.

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