• Medicina · May 2024

    Review

    The Association between Cafestol and Cardiovascular Diseases: A Comprehensive Review.

    • Wen-Rui Hao, Chun-Yao Cheng, Huan-Yuan Chen, Jin-Jer Chen, Tzu-Hurng Cheng, and Ju-Chi Liu.
    • Division of Cardiology, Department of Internal Medicine, Shuang Ho Hospital, Ministry of Health and Welfare, Taipei Medical University, New Taipei City 23561, Taiwan.
    • Medicina (Kaunas). 2024 May 26; 60 (6).

    AbstractCafestol, a bioactive compound found in coffee, has attracted considerable attention due to its potential impact on cardiovascular health. This review aims to comprehensively explore the association between cafestol and cardiovascular diseases. We delve into the mechanisms through which cafestol influences lipid metabolism, inflammation, and endothelial function, all of which are pivotal in cardiovascular pathophysiology. Moreover, we meticulously analyze epidemiological studies and clinical trials to elucidate the relationship between cafestol and cardiovascular outcomes. Through a critical examination of existing literature, we aim to provide insights into the potential benefits and risks associated with cafestol concerning cardiovascular health.

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