• Christina Cheng and Reaford Blackburn.
• Department of Internal Medicine, University of Alabama at Birmingham, 4880 Keith Drive, Birmingham, AL, 35242, USA.
• J Gen Intern Med. 2024 Aug 1; 39 (11): 211421152114-2115.

AbstractBlastomycoses dermatitidis is a dimorphic fungus that can cause disseminated blastomycosis with varying clinical manifestations and multiorgan involvement. While blastomycosis commonly causes pulmonary disease, extrapulmonary spread can result in skin, bone, and central nervous system involvement. Cutaneous blastomycosis can present as pustular lesions that evolve into ulcerative or verrucous plaques. We present a case of disseminated blastomycosis in an immunocompetent patient with both pulmonary and cutaneous features. The patient developed hypoxic respiratory failure and was subsequently diagnosed with disseminated blastomycosis after undergoing bronchoscopy with bronchial washing. He was found to have ulcerative nasal lesions as part of his disseminated disease. He was successfully treated with amphotericin B and ultimately discharged from the hospital.© 2024. The Author(s), under exclusive licence to Society of General Internal Medicine.

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