• Ana Moragas, Carolina Sarvisé, Frederic Gómez, Ester Picó-Plana, Silvia Crispi, and Carl Llor.
• Department of Medicine and Surgery, Universitat Rovira i Virgili, Tarragona, Spain; University Institute in Primary Care Research Jordi Gol, Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain; Jaume I Health Centre, Catalan Institute of Health, Tarragona, Spain.
• Aten Primaria. 2024 Jun 13; 56 (11): 102994102994.

ObjectiveThis study aimed to assess the cause of acute pharyngitis and determine the duration of severe and moderate symptoms based on the aetiology.DesignProspective observational study. SITE: One urban health care centre.ParticipantsPatients aged 15 or older with acute pharyngitis were included.InterventionsBacterial identification was carried out in the microbiology lab using MALDI-TOF in two throat samples. Patients received a symptom diary to return after one week.Main MeasurementsNumber of days with severe symptoms, scoring 5 or more in any of the symptoms included in the symptom diary, and moderate symptoms, scoring 3 or more.ResultsAmong the 149 patients recruited, beta-haemolytic streptococcus group A (GABHS) was the most common aetiology. Symptoms and signs alone as well as the mean Centor score cannot distinguish between GABHS and other bacterial causes in patients with acute pharyngitis. However, there was a trend indicating that infections caused by Streptococcus dysgalactiae and Streptococcus agalactiae presented more severe symptoms, whereas infections attributed to the Streptococcus anginosus group, Fusobacterium spp., and those where oropharyngeal microbiota was isolated tended to have milder symptoms. S. dysgalactiae infections showed a trend towards longer severe and moderate symptom duration.ConclusionGABHS was the most prevalent, but group C streptococcus caused more severe and prolonged symptoms.Copyright © 2024 The Author(s). Publicado por Elsevier España S.L.U. All rights reserved.

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