• Am. J. Surg. · Jan 1975

    Evaluation of the Nissen antireflux procedure by esophageal manometry and twenty-four hour pH monitoring.

    • T R DeMeester and L F Johnson.
    • Am. J. Surg. 1975 Jan 1; 129 (1): 9410094-100.

    AbstractFifteen normal volunteers without symptoms of gastroesophageal reflux and sixteen patients with symptoms of gastroesophageal reflux unresponsive to medical management and having endoscopic esophagitis had esophageal manometry and twenty-four hour pH monitoring of the distal esophagus. The symptomatic patients underwent a Nissen antireflux procedure and were restudied at four months. After surgery, patients had less reflux, a higher sphincteric pressure, and an equal amount of sphincter within the abdomen as did asymptomatic control subjects.

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