• Revista médica de Chile · Jun 2023

    Case Reports

    [Managing Superwarfarin Poisoning: A Challenging Case].

    • Giovanna Zavadzki, José Inzunza Robles, María Fernanda San Martín, Waldo Gutiérrez Torres, José Tomás Ramos-Rojas, Jamil Gauna-Cordero, and Natalia Bigossi Aguiar.
    • Hospital Dr Sótero del Río, Fundación Epistemonikos, Universidad Federal de Sao Paulo, Brasil.
    • Rev Med Chil. 2023 Jun 1; 151 (6): 797800797-800.

    AbstractHuman intoxication by long-acting anticoagulant rodenticides, known as superwarfarins, causes coagulopathy that is difficult to manage. We present the case of a 42-year-old man who ingested a toxic dose of rodenticide in a suicide attempt, evolving with epistaxis, INR of 11.6, and needing hospitalization. For seven days, serial controls of coagulation tests were carried out, with optimization of different doses of Vitamin K supplementation. The case highlights this type of anticoagulant's potency and prolonged half-life (approximately six weeks), which requires regular clinical control and satisfactory treatment adherence.

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