• Richard Chocron, Thomas Laurenceau, Tal Soumagnac, Frankie Beganton, Patricia Jabre, and Xavier Jouven.
• Paris Cité University, Paris Research Cardiovascular Center (PARCC), INSERM, F-75015 Paris, France; Emergency Department, Assistance Publique des Hôpitaux de Paris (AP-HP), Georges Pompidou European Hospital, F-75015 Paris, France. Electronic address: richard.chocron@aphp.fr.
• Resuscitation. 2024 Aug 1; 201: 110318110318.

ImportanceUncontrolled donation after circulatory determination of death (uDCD) has been developed and can serve as a source of kidneys for transplantation, especially when considering patients that meet extended criteria donation (ECD).ObjectiveThis study assessed the theorical size and characteristics of the potential pool of kidney transplants from uDCD with standard criteria donation (SCD) and ECD among patients who meet Termination of Resuscitation (TOR) criteria following Out of Hospital Cardiac Arrest (OHCA).Methods And ParticipantsThis study focused on adult patients experiencing unexpected OHCA, who were prospectively enrolled in the Parisian registry from May 16th, 2011, to December 31st, 2020.ResultsDuring the study period, EMS attempted resuscitation for 19,976 OHCA patients, of which 64.5% (12,890) had no return of spontaneous circulation. Among them, 47.4% (9,461) had TOR criteria, representing no chance of survival, and from them, 8.8% (1,764) met SCD criteria and could be potential organ donors and 33.6% (6,720) met ECD for kidney donors. The mean potential number per year of uDCD candidates with SCD and ECD remain stable respectively around 98 (±10.8) and 672 (±103.8) cases per year. Elderly patients (≥65 y.o.) represented 61.2% (n = 5,763/9,461) of patients who met TOR and 100% (5763/5763) of patients who could have matched both ECD criteria and TOR.Conclusion And RelevanceImplementing uDCD program including SCD and ECD for kidney transplantation among OHCA cases quickly identified by the TOR, holds significant potential to substantially broaden the pool of organ donors. These programs could offer a viable solution to address the pressing burden of kidney shortage, particularly benefiting elderly recipients who may otherwise face prolonged waiting times and limited access to suitable organs.Copyright © 2024 The Author(s). Published by Elsevier B.V. All rights reserved.

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