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- Nao Nomura, Akira Také, Haruki Uojima, Yoshihiko Sakaguchi, Kazuyoshi Gotoh, Takashi Satoh, Hisashi Hidaka, Kazue Horio, Masashi Mizokami, Shunji Hayashi, and Chika Kusano.
- Department of Gastroenterology, Internal Medicine, Kitasato University School of Medicine, Japan.
- Intern. Med. 2024 Jul 4.
AbstractWe herein report a 67-year-old Japanese woman with liver cirrhosis caused by primary biliary cholangitis. The patient was admitted to the hospital with loss of consciousness. Hepatic encephalopathy (HE) was diagnosed after diagnostic imaging and symptom assessments. Molecular biology tests were performed on oral saliva and stool samples. The test results indicated sequence similarity between urease-positive S. salivarius in both oral saliva and stool, as revealed by the signals in the overlapping peaks. This bacterium can potentially increase ammonia production in the gut, leading to HE in patients with liver cirrhosis.
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