• Wenyang Pang, Zhengyi Wang, Xiaoyan Jin, and Qiang Zhang.
• Department of Oncology Surgery, The Taizhou Municipal Hospital, Taizhou University, Taizhou, Zhejiang, China.
• Medicine (Baltimore). 2019 Aug 1; 98 (32): e16760e16760.

RationaleAdenoid cystic carcinoma (ACC) of the breast is an infrequent neoplasm, and the occurrence in males is rare. Therefore, diagnostic and therapeutic challenges are inevitable.Patient ConcernsHerein, we present a case of a 44-year-old man with a tumor on his right breast that he had known about for 6 years.DiagnosesThe patient underwent a lumpectomy, and the histological examination confirmed a diagnosis of ACC.InterventionsModified radical mastectomy was subsequently conducted in the patient. No positive lymph nodes were observed in the postoperative pathological examination. Following the surgery, the patient received adjuvant chemotherapy.OutcomesThe patient remained recurrence-free at 26 months.LessonsCompared to female breast ACC, male breast ACC may behave differently biologically and have a different prognosis. Our case will provide more diagnostic and treatment experience to deal with this disease.

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