• Int J Med Sci · Jan 2019

    Review

    Papillary Thyroid Cancer: Genetic Alterations and Molecular Biomarker Investigations.

    • Mardiaty Iryani Abdullah, Sarni Mat Junit, Khoon Leong Ng, Jaime Jacqueline Jayapalan, Barani Karikalan, and Onn Haji Hashim.
    • Department of Molecular Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.
    • Int J Med Sci. 2019 Jan 1; 16 (3): 450460450-460.

    AbstractPapillary thyroid cancer (PTC) is the most prevalent form of malignancy among all cancers of the thyroid. It is also one of the few cancers with a rapidly increasing incidence. PTC is usually contained within the thyroid gland and generally biologically indolent. Prognosis of the cancer is excellent, with less than 2% mortality at 5 years. However, more than 25% of patients with PTC developed a recurrence during a long term follow-up. The present article provides an updated condensed overview of PTC, which focuses mainly on the molecular alterations involved and recent biomarker investigations.

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