• Rev Assoc Med Bras (1992) · Jan 2024

    The role of serum adropin in determining the clinical outcomes of patients with traumatic brain injury: a case-control study.

    • Özlem Tataroğlu, Oya Güven, İlhami Demirel, Özgür Söğüt, Mehmet Yiğit, Olgun Demir, and Esma Özdemir Anayurt.
    • University of Health Sciences, Dr. Lütfi Kırdar City Hospital, Department of Emergency Medicine - İstanbul, Turkey.
    • Rev Assoc Med Bras (1992). 2024 Jan 1; 70 (7): e20240275e20240275.

    ObjectiveIt has been determined that adropin has a role in tissue healing. This study aimed to determine the effects of head trauma on the tissues and blood levels of patients admitted to the emergency department.MethodsThe study group was divided into two to compare the adropin level in healthy individuals and patients with head trauma. Blood tests from patients and healthy volunteers were compared using the adropin kit. Adropin levels, Glasgow Coma Scale, and revised scores of trauma patients were recorded and analyzed.ResultsAll patients in the trauma group had significantly higher adropin levels than the control group. Among these patients, the adropin level of the discharged patients was higher than the others. In addition, patients with high Glasgow Coma Scale and normal blood pressure were found to have higher adropin levels than the others.ConclusionAlthough adropin cannot make a sharp distinction in determining the prognosis, the increase in its level in trauma patients shows that it triggers a protective mechanism.

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