• Yani Fan, Yue Lv, Meng Fu, Jianhua Wang, Ying Cui, Binbin Zhang, Yadan Lu, and Lili Chen.
• Tangshan Gongren Hospital, Tangshan City, Hebei Province, China.
• Ir J Med Sci. 2024 Oct 1; 193 (5): 250125072501-2507.

ObjectiveIn this study, the relationship between maximum carotid plaque area and stroke prognosis was analysed by carotid ultrasonography, and the relevant risk factors affecting the prognosis of acute ischaemic stroke (AIS) were investigated to provide novel insights into stroke prevention and management.MethodsA total of 205 AIS patients with carotid plaques were included in this study. Based on the mRS score at discharge, patients with AIS were classified into the good prognosis group (mRS ≤ 2) and poor prognosis group (mRS ≥ 3). SPSS 25.0 was used to analyse the data. Univariate and multivariate analyses were performed on the two groups with good and poor prognosis. Comparison between good and poor prognosis in patients with AIS in different circulatory systems was performed using the Kruskal-Wallis test. Differences were considered statistically significant at P < 0.05.ResultsComparison of baseline data revealed differences in carotid plaque diameter, carotid intima-media thickness, maximum carotid plaque area, history of previous stroke and plaque echogenicity between the good and poor prognosis groups (P < 0.05). Results of multifactorial analyses of logistic binary regression indicated that history of previous stroke and maximum carotid plaque area were predictors of poor prognosis, with odds ratio of 2.515 (95%CI [1.327-4.764]) and 1.019 (95%CI [1.006-1.032]), respectively.ConclusionThe maximum carotid plaque area and history of previous stroke are important predictors for assessing prognosis in patients with AIS.© 2024. The Author(s), under exclusive licence to Royal Academy of Medicine in Ireland.

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