• Yani Fan, Sujie Wang, Yue Lv, Guoyan Shi, Yadan Lu, and Lili Chen.
• Tangshan Gongren Hospital, Tangshan City, Hebei Province, China.
• Ir J Med Sci. 2024 Oct 1; 193 (5): 250925142509-2514.

ObjectiveTo validate the predictive performance of the THRIVE, ASTRAL, and iScore scales for clinical functional outcomes following mechanical thrombectomy (MT) for acute ischemic stroke (AIS).MethodsA total of 111 patients meeting the inclusion criteria were included in this study, with 59 (53.2%) having a good prognosis and 52 (46.8%) having a poor prognosis. MedCalc software was applied to plot receiver operating characteristic (ROC) curves, calculate the area under the curve (AUC), and compare the predictive efficacy of the three scales two by two using Delong text. Statistical significance was defined as Pc < 0.05.ResultsLogistic binary regression multifactorial analysis revealed that iScore is one of the poor predictors of prognosis in patients with MT. The AUC values for the THRIVE, ASTRAL, and iScore scales in predicting prognosis after MT were found to be 0.713, 0.738, and 0.820, respectively.ConclusionThe iScore is a reliable tool for assessing the poor prognosis of MT in patients with AIS.© 2024. The Author(s), under exclusive licence to Royal Academy of Medicine in Ireland.

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