• Frank C Detterbeck, Gavitt A Woodard, Anna S Bader, Sanja Dacic, Michael J Grant, Henry S Park, and Lynn T Tanoue.
• Division of Thoracic Surgery, Department of Surgery, Yale University School of Medicine, New Haven, CT. Electronic address: frank.detterbeck@yale.edu.
• Chest. 2024 Oct 1; 166 (4): 882895882-895.

AbstractA universal nomenclature of the anatomic extent of lung cancer has been critical for individual patient care as well as research advances. As progress occurs, new details emerge that need to be included in a refined system that aligns with contemporary clinical management issues. The ninth edition TNM classification of lung cancer, which is scheduled to take effect in January 2025, addresses this need. It is based on a large international database, multidisciplinary input, and extensive statistical analyses. Key features of the ninth edition include validation of the significant changes in the T component introduced in the eighth edition, subdivision of N2 after exploration of fundamentally different ways of categorizing the N component, and further subdivision of the M component. This has led to reordering of the TNM combinations included in stage groups, primarily involving stage groups IIA, IIB, IIIA, and IIIB. This article summarizes the analyses and revisions for the TNM classification of lung cancer to familiarize the broader medical community and facilitate implementation of the ninth edition system.Copyright © 2024 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

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