• Curr Opin Anaesthesiol · Oct 2024

    Meta Analysis

    Perioperative care of patients with recent stroke undergoing nonemergent, nonneurological, noncardiac, nonvascular surgery: a systematic review and meta-analysis.

    • Abhijit V Lele, Elizabeth Olive Moreton, Jayashree Sundararajan, and Samuel Neal Blacker.
    • Department of Anesthesiology and Pain Medicine, University of Washington, Harborview Medical Center, Seattle, Washington.
    • Curr Opin Anaesthesiol. 2024 Oct 1; 37 (5): 460469460-469.

    Purpose Of ReviewTo systematically review and perform a meta-analysis of published literature regarding postoperative stroke and mortality in patients with a history of stroke and to provide a framework for preoperative, intraoperative, and postoperative care in an elective setting.Recent FindingsPatients with nonneurological, noncardiac, and nonvascular surgery within three months after stroke have a 153-fold risk, those within 6 months have a 50-fold risk, and those within 12 months have a 20-fold risk of postoperative stroke. There is a 12-fold risk of in-hospital mortality within three months and a three-to-four-fold risk of mortality for more than 12 months after stroke. The risk of stroke and mortality continues to persist years after stroke. Recurrent stroke is common in patients in whom anticoagulation/antiplatelet therapy is discontinued. Stroke and time elapsed after stroke should be included in the preoperative assessment questionnaire, and a stroke-specific risk assessment should be performed before surgical planning is pursued.SummaryIn patients with a history of a recent stroke, anesthesiology, surgery, and neurology experts should create a shared mental model in which the patient/surrogate decision-maker is informed about the risks and benefits of the proposed surgical procedure; secondary-stroke-prevention medications are reviewed; plans are made for interruptions and resumption; and intraoperative care is individualized to reduce the likelihood of postoperative stroke or death.Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.

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