• Alexander A Chernysh, David H Loftus, Bryan Zheng, Jonathan Arditi, Owen P Leary, and Jared S Fridley.
• Warren Alpert Medical School of Brown University, Rhode Island Hospital, Department of Neurosurgery, Providence, Rhode Island, USA. Electronic address: alexander.a.chernysh@gmail.com.
• World Neurosurg. 2024 Oct 1; 190: 889888-98.

ObjectiveAs advances are made in quantitative magnetic resonance imaging, specifically diffusion tensor imaging, researchers have investigated its potential to serve as a biomarker of disease or prognosticator for postoperative recovery in the management of cervical spondylotic myelopathy. Here, we narratively review the current state of the emerging literature, describing areas of consensus and disagreement.MethodsIn accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses, we queried 2 large databases for original manuscripts published in English and systematically produced a narrative review of the use of diffusion tensor imaging in the management of cervical spondylotic myelopathy.ResultsOf the 437 manuscripts initially returned in our query, 29 met the final inclusion criteria, and data were extracted regarding diffusion tensor imaging indices and their relationships with clinical outcomes following surgery. Preoperative fractional anisotropy was most commonly found to correlate closely with postsurgical clinical outcomes, though results were mixed.ConclusionsPreoperative fractional anisotropy most frequently and best correlates with functional outcomes following surgery for cervical spondylotic myelopathy, according to a review of the current literature. The findings were not universal and at times contradictory, highlighting the need for high-quality future investigations to better define the utility of diffusion tensor imaging in spinal disease.Copyright © 2024 Elsevier Inc. All rights reserved.

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