• Daolong Li, Jun Shen, Zhenshi Yang, Yuzhong Zhang, and Zhiyong Li.
• Department of Neurosurgery, Affiliated Hospital of West Anhui Health Vocational College, Lu'an, Anhui, China; Department of Neurosurgery, Lu'an Second People's Hospital, Lu'an, Anhui, China. Electronic address: ldlendo@126.com.
• World Neurosurg. 2024 Oct 1; 190: e243e248e243-e248.

BackgroundDespite effective treatment for aneurysmal subarachnoid hemorrhage (aSAH), delayed cerebral ischemia (DCI) is a common complication that has a significant impact on the recovery of neurologic function. In this study, we aimed to investigate the efficacy of hyperbaric oxygen therapy (HBOT) in the rehabilitation treatment of aSAH.MethodsIn this study, a total of 98 patients with aSAH and 25 healthy individuals were recruited. The patients included 51 who received HBOT after the effective treatment of aSAH and 47 who received only physical rehabilitation. The modified Rankin Scale (mRS) and Mini-Mental Status Examination (MMSE) were applied for all patients at 7 days after aSAH to determine baseline neurologic deficits and cognitive function. The Attention Network Test (ANT) was performed at the sixth month.ResultsThe results indicated that the patients receiving HBOT had a lower incidence of DCI (P = 0.026) and better improvement of executive control function (P < 0.001) of ANT compared to those without HBOT. However, there were no differences in orienting, alerting, mean reaction time, and accuracy between the 2 groups.ConclusionsIn summary, early HBOT reduced the DCI rate in aSAH patients and consequently promoted improvement of the executive control function of ANT.Copyright © 2024 Elsevier Inc. All rights reserved.

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