• Medicina clinica · Jul 2024

    Review

    Characterization of bone disease in cystic fibrosis.

    • Victoria Contreras-Bolívar, María Carmen Andreo-López, and Manuel Muñoz-Torres.
    • Endocrinology and Nutrition Unit, University Hospital Clínico San Cecilio, 18016 Granada, Spain; Instituto de Investigación Biosanitaria de Granada (Ibs. Granada), 18014 Granada, Spain; CIBER on Frailty and Healthy Aging (CIBERFES), Instituto de Salud Carlos III, 18012 Granada, Spain.
    • Med Clin (Barc). 2024 Jul 16.

    AbstractWith the increased life expectancy of people with cystic fibrosis (CF), clinical attention has focused on prevention and treatment of non-pulmonary comorbidities. CF-related bone disease (CFBD) is a common complication and leads to increased fracture rates. Dual energy X-ray absorptiometry (DXA) is the recommended and gold standard technique to identify and monitor bone health. However, DXA has limitations because of its two-dimensional nature. Complementary tools to DXA are available, such as trabecular bone score (TBS) and vertebral fracture assessment (VFA). Quantitative computed tomography (QCT), magnetic resonance imaging (MRI) and quantitative ultrasound (QUS) may also be useful.Copyright © 2024 Elsevier España, S.L.U. All rights reserved.

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