• Medicina clinica · Jul 2024

    Review

    Etiology of hypophosphatemia in adults.

    • Nuria Puente Ruiz, M Carmen Valero Díaz de Lamadrid, and José A Riancho.
    • Servicio de Medicina Interna, Hospital Universitario Marqués de Valdecilla; Departamento de Medicina y Psiquiatría, Universidad de Cantabria; Instituto de Investigación Marqués de Valdecilla (IDIVAL), Santander, España; Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER, ISCIII), Madrid, España. Electronic address: nuria.puente@scsalud.es.
    • Med Clin (Barc). 2024 Jul 17.

    AbstractLong-term hypophosphatemia, defined by serum phosphorus (P) levels <2.5mg/dL, impairs the development and quality of mineralized tissue of the skeletal, dental, and auditory systems. P homeostasis depends mainly on intestinal absorption and renal excretion. Hypophosphatemia may be due to the redistribution of P to the intracellular space, increased renal losses, or decreased intestinal absorption. Hypophosphatemia can be categorized as acute or chronic, depending on the time course. Most cases, either acute or chronic, are due to acquired causes. However, some chronic cases may have a genetic origin. Accurate and early diagnosis, followed by adequate treatment, is essential to limit its negative effects on the body.Copyright © 2024 Elsevier España, S.L.U. All rights reserved.

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