• Sakiko Yamaguchi, Alix Zerbo, Roberta Cardoso, Mayada Elsabbagh, Aryeh Gitterman, Stephanie Glegg, Miriam Gonzalez, Connie Putterman, Jonathan A Weiss, Keiko Shikako, and CHILD‐BRIGHT Knowledge Translation Program Committee.
• School of Physical and Occupational Therapy, McGill University, Montreal, Quebec, Canada.
• J Eval Clin Pract. 2024 Dec 1; 30 (8): 147714891477-1489.

RationaleThe Knowledge Translation (KT) Programme of a pan-Canadian strategic patient-oriented research network focused on brain-based developmental disabilities aimed to mobilize knowledge relevant to the network members. The programme also promotes and studies integrated Knowledge Translation (iKT) approaches involving different interested parties, such as researchers, patient-partners and decision-makers, in all parts of the knowledge creation process.Aims And ObjectivesThe objective of this study is to advance research programme evaluation methods through a realist evaluation of the process of implementing iKT activities.MethodsRealist process evaluation included: (1) development of initial programme theories (using the partnership synergy theory); (2) data collection and analysis; (3) synthesis and refinement of theories through engagement with literature; and (4) presentation of findings in context-mechanism-outcome (C-M-O) configurations. A range of project documentation records were reviewed for analysis, and three co-leads, a programme coordinator, and a senior research associate were consulted to contextualize the implementation process of relevant KT activities.ResultsBased on the developed C-M-O configurations, we identified five key mechanisms of generating synergy in the iKT processes: (1) Visible shared leadership that embodies what iKT looks like; (2) Researchers' readiness for iKT; (3) Adaptation and flexible allocation of resources to emerging needs; (4) Power sharing to create practical and creative knowledge; and (5) Collective voice for potential transformative impacts at the policy level.ConclusionsThe current realist evaluation demonstrated how partnerships between researchers, patient-partners and other interested parties can synergistically generate new ways of thinking among all interested parties, actionable strategies to integrate users in research, and solutions to disseminate knowledge. In particular, we identified a pivotal role for patient-partners to act as equal decision-maker helps building and maintaining partnerships and consolidating KT strategies.© 2024 The Author(s). Journal of Evaluation in Clinical Practice published by John Wiley & Sons Ltd.

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