• Pietro Gentile, Barbara De Angelis, Methap Pasin, Giulio Cervelli, Cristiano B Curcio, Micol Floris, Camilla Di Pasquali, Ilaria Bocchini, Alberto Balzani, Fabio Nicoli, Chiara Insalaco, Eleonora Tati, Lucilla Lucarini, Ludovico Palla, Michele Pascali, Pamela De Logu, Chiara Di Segni, Davide J Bottini, and Valerio Cervelli.
• From the *Department of Plastic and Reconstructive Surgery, University of Rome Tor Vergata; †Department of Immunohematology and Transfusion, Casilino Hospital; and ‡Department of Education, University of Rome Tor Vergata, Rome, Italy.
• J Craniofac Surg. 2014 Jan 1;25(1):267-72.

BackgroundActually, autologous fat grafts have many clinical applications in breast surgery, facial rejuvenation, buttock augmentation, and Romberg syndrome as well as a treatment of liposuction sequelae.ObjectiveThe aim of this article was to describe the preparation and isolation procedures for stromal vascular fraction (SVF), the preparation of platelet-rich plasma (PRP), and the clinical application in the treatment of the scar on the face.MethodsTen patients with burns sequelae (n = 6) and post-traumatic scars (n = 4) were treated with SVF-enhanced autologous fat grafts obtained by the Celution System. Another 10 patients with burns sequelae (n = 5) and post-traumatic scars (n = 5) were treated with fat grafting based on the Coleman technique mixed with 0.5 mL of PRP.To assess the effects of their treatment, the authors compared their results with those of a control group consisting of 10 patients treated with centrifuged fat.ResultsIn the patients treated with SVF-enhanced autologous fat grafts, we observed a 63% maintenance of contour restoring after 1 year compared with only 39% of the control group (n = 10) treated with centrifuged fat graft (P < 0.0001). In the patients treated with fat grafting and PRP, we observed a 69% maintenance of contour restoring after 1 year compared with that of the control group (n = 10).ConclusionsAutologous fat grafting is a good method for the correction of scars on the face instead of the traditional scar surgical excision.

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