• J. Clin. Gastroenterol. · Jul 2003

    Case Reports

    Acute viral cholecystitis due to hepatitis A virus infection.

    • Resat Ozaras, Ali Mert, Mehmet Halit Yilmaz, Aygul Dogan Celik, Fehmi Tabak, Muammer Bilir, and Recep Ozturk.
    • Department of Infectious Diseases and Clinical Microbiology, Cerrahpasa Medical Faculty, 34303 Cerrahpasa, Istanbul, Turkey. rozaras@yahoo.com
    • J. Clin. Gastroenterol. 2003 Jul 1;37(1):79-81.

    AbstractAcute hepatitis A virus (HAV) infection is frequent in developing countries. Although some gallbladder abnormalities are defined during the course, an acute cholecystitis is extremely rare. We here report 2 additional cases of cholecystitis due to acute HAV infection and review the previously reported 2 cases. One of our patients was admitted with jaundice and a suspicious portal mass with a presumed diagnosis of cholagiocarcinoma. The other presented with jaundice, abdominal pain, and constitutional symptoms. Both patients were planned to be operated on. During the follow-up, absence of fever, leukocytosis, acute-phase protein response, and calculus in biliary system were against the diagnosis of a bacterial cholecystitis. Moreover the course of cholecystitis was closely parallel to that of the HAV infection. Both patients were managed conservatively. It was concluded that rare, acute viral cholecystitis can develop during the course of acute HAV infection.

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