• María Victoria Díaz-Franco, Susane Díaz, Katherine Hernández Carrasco, Bárbara Peña Curinao, Javiera Sandoval Urrea, Jamileth Silva Montecinos, and Alexis Caniuqueo-Vargas.
• Carrera de Fonoaudiología, Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Temuco, Chile.
• Rev Med Chil. 2023 Sep 1; 151 (9): 112511421125-1142.

IntroductionVarious studies have linked lifestyle and metabolic diseases to hearing loss. Research on metabolic syndrome has reported a higher prevalence of hearing loss in individuals with it than those without it.ObjectivesTo conduct a systematic review and meta-analysis summarizing the risk of hearing loss in people diagnosed with metabolic syndrome or diseases versus those without metabolic syndrome.MethodsFollowing the PRISMA recommendations for systematic review and meta-analysis, searches were conducted in PubMed, Web of Science, and SciELO. Only cross-sectional studies associate hearing loss with obesity, hypertension, Diabetes, Dyslipidemia, Cholesterol, metabolic syndrome, and Hyperglycemia. The odds ratios (OR) with their 95% confidence intervals (CI) of the studies were pooled in a random effects model using the Mantel-Haenszel method. Using Rev Manager 5.1, OR heterogeneity was assessed using the I2 and Q statistics.ResultsTwenty-eight observational studies were included in the quantitative analysis. The OR for prevalent hearing loss was 1.27 (95% CI 1.07, 1.51) in obesity, 1.97 (95% CI 1.51, 2.57) in diabetes, 1.53 (95% CI 1.31, 1.79) in hypertension, and 4.22 (95% CI 1.74, 10.20) for metabolic syndrome.ConclusionsThe findings suggest that both metabolic syndrome and some diseases, such as obesity, diabetes, and hypertension, could be associated with the risk of hearing loss, and control of these diseases could reduce this risk.

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