• Revista médica de Chile · Sep 2023

    Review

    [Advances in Nasopharyngeal Carcinoma Treatment: Induction Chemotherapy and Concomitant Radio-Chemotherapy].

    • Felipe Carvajal, Gustavo Luyo, Javier Veloso, Marcelo Veloso, Freddy Alarcón, Eduardo Villa, and Erika Saavedra.
    • Instituto Nacional del Cáncer, Santiago, Chile.
    • Rev Med Chil. 2023 Sep 1; 151 (9): 122112321221-1232.

    AbstractSquamous cell carcinoma of the nasopharynx is responsible for 0.7% of all malignant tumors worldwide, with the highest incidence in the population of southern China and Southeast Asia. The standard treatment for locally advanced disease consists of a combination of radiotherapy and chemotherapy in different schedules. Among them, induction chemotherapy followed by concomitant radio-chemotherapy has shown in recent years to be a standard therapeutic option with high rates of locoregional control and overall survival. This paper aims to review the current evidence related to treatment with induction chemotherapy and subsequent radio-chemotherapy in nasopharyngeal cancer, its effectiveness, and the technical aspects of its applicability.

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