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Review
Biological and Clinical Characteristics of Proximal Colon Cancer: Far from Its Anatomical Subsite.
- Qing Yang, Ruize Qu, Siyi Lu, Yi Zhang, Zhipeng Zhang, and Wei Fu.
- Department of General Surgery, Peking University Third Hospital, Beijing China.
- Int J Med Sci. 2024 Jan 1; 21 (10): 182418391824-1839.
AbstractColorectal cancer is a heterogeneous disease which can be divided into proximal colon cancer, distal colon cancer and rectal cancer according to the anatomical location of the tumor. Each anatomical location of colorectal cancer exhibits distinct characteristics in terms of incidence, clinical manifestations, molecular phenotypes, treatment, and prognosis. Notably, proximal colon cancer differs significantly from cancers of other anatomical subsites. An increasing number of studies have highlighted the presence of unique tumor biological characteristics in proximal colon cancer. Gaining a deeper understanding of these characteristics will facilitate accurate diagnosis and treatment approaches.© The author(s).
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