• Cochrane Db Syst Rev · Aug 2024

    Meta Analysis

    Alcohol consumption and heart failure: a dose-response meta-analysis.

    • Bethany Wong, Cristin Ryan, Adeniyi Fagbamigbe, Jonathan Jh Bray, Bernard McNamee, Vikram Niranjan, Shuaiwei Zhou, Delia Bogdanet, Catriona Reddin, Ken McDonald, and Mark Ledwidge.
    • School of Medicine and Medical Science, University College Dublin, Dublin, Ireland.
    • Cochrane Db Syst Rev. 2024 Aug 9; 8 (8): CD015398CD015398.

    AbstractThis is a protocol for a Cochrane Review (prototype). The objectives are as follows: Main objective To assess the effects of alcohol consumption on the progression to symptomatic (stage C) heart failure in people at risk for heart failure (stage A) or in people with pre-heart failure (stage B). Secondary objectives To assess the effects of alcohol consumption on progression of left ventricular dysfunction in people with stage A or stage B heart failure. We will assess the effect of alcohol consumption on the development of heart failure with reduced ejection fraction, mildly reduced ejection fraction, and preserved ejection fraction. We also aim to evaluate the effects of alcohol consumption on the development of symptomatic (stage C) heart failure over the short, medium and long term.Copyright © 2024 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

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