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- Takuro Shiga, Shun Ishiyama, Naoto Sugeno, Kei Nozue, Kazuo Kakinuma, and Masashi Aoki.
- Department of Neurology, Tohoku University Graduate School of Medicine, Japan.
- Intern. Med. 2024 Aug 10.
AbstractProgressive supranuclear palsy (PSP) is characterized by progressive postural instability, falls, and supranuclear vertical gaze abnormalities. In this report, we present the case of a 71-year-old woman with dopa-responsive rest tremor followed by tachyphemia and postural instability. She initially presented with dopa-responsive slowness and tremor in the right hand. Two years later, she developed speech difficulties (tachyphemia) and a propensity for falls. Based on the diagnostic criteria for PSP, the patient was diagnosed with probable PSP-RS. The clinical manifestations observed in our patient are unique and are considered important for illustrating a broad spectrum of PSP syndrome.
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