• Dtsch. Med. Wochenschr. · Aug 2024

    [Chronic HBV and HDV infection].

    • Giuseppe Rusignuolo, Robert Thimme, and Christoph Neumann-Haefelin.
    • Dtsch. Med. Wochenschr. 2024 Aug 1; 149 (16): 948954948-954.

    AbstractAbout 0,5% of the population in Germany has a chronic hepatitis B virus (HBV) infection. Untreated, chronic HBV infection can progress to liver cirrhosis and hepatocellular carcinoma (HCC). If diagnosed early, antiviral therapy can effectively prevent liver disease progression, but a cure is currently hardly achievable. About 5% of those chronically infected with HBV are also co-infected with the hepatitis D virus (HDV). HBV/HDV co-infection leads to liver cirrhosis in approximately 50% of patients within 5-10 years. Since 2020, the cell entry inhibitor bulevirtide is available as a specific therapy for HBV/HDV co-infection.Thieme. All rights reserved.

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