• Lu Zhang, Xi Yang, Yuanyuan Zhang, Yaru Wen, Manni Huang, and Jusheng An.
• Department of Gynecological Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
• Medicine (Baltimore). 2024 Aug 9; 103 (32): e39275e39275.

RationaleCervical metastasis of breast cancer is rare and its clinical manifestations are similar to those of primary cervical cancer. It is thus easy to misdiagnose, with diagnosis mainly depending on pathology and immunohistochemistry. There have been few studies on its treatment and there is thus no standard treatment plan.Patient ConcernsThis is a 64-year-old female patient presented with a 2-month history of abnormal postmenopausal vaginal discharge, who had previous history of breast cancer.DiagnosesBased on the gynecological examination, imaging results, pathology, and immunohistochemical results, a diagnosis of metastatic carcinoma of the cervix and breast cancer was confirmed.InterventionsShe received computed tomography-guided 3-dimensional high-dose-rate brachytherapy in combination with chemotherapy.OutcomesShe achieved complete response locally. This case provides a new local treatment option for patients with inoperable localized cervical metastases.LessonsWe hope that this report and the accompanying review help to enrich the literature pertaining to the treatment of rare cervical metastases, providing a foundation for the improved survival of affected patients.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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