• Medicine · Aug 2024

    Review Case Reports

    Hyalinizing clear cell carcinoma in the nasopharynx: A case report and literature review.

    • Yu-Wei Chang and Hsing-Mei Wu.
    • Department of Otolaryngology, Shin-Kong Wu-Ho-Su Memorial Hospital, Taipei, Taiwan.
    • Medicine (Baltimore). 2024 Aug 9; 103 (32): e39163e39163.

    RationaleHyalinizing clear cell carcinoma (HCCC) arising from a minor salivary gland is a rare malignant neoplasm. Most HCCC has been reported in the palate and tongue base, and only rarely in the nasopharynx. Here, we report a rare case of nasopharyngeal HCCC.Patient ConcernsA 44-year-old male who complained of otorrhea and aural fullness for 5 years was found to have a nasopharyngeal mass.DiagnosesHCCC by fluorescence in situ hybridization analysis.InterventionsSurgical resection plus concurrent chemotherapy and radiation therapy were administered.OutcomesThe patient recovered well with symptoms improved at postoperative follow-up.LessonsHCCC should be included in the differential diagnosis of nasopharyngeal mass. Overall, the prognosis of HCCC is positive after tumor resection and adequate management.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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