• Yanan Li, Yifan Dang, Yanhui Zhou, Haidong Wang, Lisheng Zheng, and Yudong Ba.
• Department of Blood Transfusion, Dongying People's Hospital (Dongying Hospital of Shandong Provincial Hospital Group), Dongying, People's Republic of China.
• Medicine (Baltimore). 2024 Aug 9; 103 (32): e39256e39256.

AbstractIron metabolism plays an important role in insulin resistance, and the triglyceride-glucose (TyG) index has been proposed in recent years as a more accessible and cost-effective marker for insulin resistance. This study aims to evaluate the association between iron metabolism markers, including ferritin (FER), transferrin (TRF), and transferrin receptor (TFR), and the TyG index. A total of 6524 Chinese individuals aged between 18 and 75 years were included in this study. Multivariable linear models were used to investigate the association between FER, TRF, and TFR levels, and the TyG index. Further subgroup analyses stratified by age and sex were also performed. There was a positive association between FER and TRF levels and the TyG index in all 3 multivariable linear regression models, regardless of stratification by sex and age. Additionally, TFR was positively associated with the TyG index among females and those aged ≥45 years, but not among males and those aged <45 years. Our findings reveal a positive association between FER and TRF levels and the TyG index in a Chinese population, while the association between TFR levels and the TyG index showed different patterns depending on age and gender.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

30 keywords...

hide…