• Medicina · Jun 2024

    Review

    An Overview of Methotrexate Indications in Skin Diseases.

    • Mădălina Mocanu, Dorina Procopciuc, Dragoș-Florin Gheucă-Solovăstru, Ioana Adriana Popescu, Doinița Temelie Olinici, Adriana Ionela Pătrașcu, Dan Vâță, and Laura Gheucă-Solovăstru.
    • Department of Dermatology, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
    • Medicina (Kaunas). 2024 Jun 21; 60 (7).

    AbstractMethotrexate is an immunosuppressive drug with remarkable therapeutic results in the treatment of autoimmune and proliferative skin diseases. Although it has been more than half a century since it was first introduced into the therapeutic arsenal of dermatologists, there are currently no standardized therapeutic protocols regarding the prescription of methotrexate in dermatology, with the exception of psoriasis treatment. This review aims to highlight the indications and benefits of methotrexate beyond psoriasis, with a focus on a wide range of inflammatory, vesiculobullous, and proliferative dermatological pathologies.

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