-
Case Reports
Multisite distribution of fibrillary inclusions in a patient with light chain proximal tubulopathy: A case report.
- Yingying Wang, Kai Chen, Shengguo Zhou, and Wei Zhang.
- Department of Nephrology, Jining No. 1 People's Hospital, Jining, Shandong, China.
- Medicine (Baltimore). 2024 Aug 16; 103 (33): e39174e39174.
RationaleLight chain proximal tubulopathy (LCPT) is a rare form of renal impairment associated with multiple myeloma (MM). LCPT is caused by inclusions formed of free light chains that are typically crystalline, but can also be noncrystalline structures.Patient ConcernsA 62-year-old man was hospitalized for the investigation of abnormal urine test results lasting for 1 year and kidney-function abnormalities persisting for more than 1 month.DiagnosesNoncrystalline LCPT and MM.InterventionsThe patient was treated with the lenalidomide, bortezomib, and dexamethasone and pomalidomide, bortezomib, and dexamethasone chemotherapy regimens.OutcomesComplete remission of MM was achieved, and the patient's renal function returned to normal.LessonsThis case report highlights the importance of renal pathology in the diagnosis of patients with unexplained chronic kidney disease and proteinuria.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*,_underline_or**bold**. - Superscript can be denoted by
<sup>text</sup>and subscript<sub>text</sub>. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3., hyphens-or asterisks*. - Links can be included with:
[my link to pubmed](http://pubmed.com) - Images can be included with:
 - For footnotes use
[^1](This is a footnote.)inline. - Or use an inline reference
[^1]to refer to a longer footnote elseweher in the document[^1]: This is a long footnote..