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- Emily Nicholson, Tom Jaconelli, and Steven Crane.
- Department of Emergency Medicine, York Hospital, York, North Yorkshire, UK.
- Emerg Med J. 2024 Oct 23; 41 (11): 700701700-701.
AbstractA shortcut review of the literature was carried out to examine whether the measurement of neuron-specific enolase (NSE) can be used as a marker to exclude spinal cord, cauda equina or other significant spinal nerve root compression. 132 papers were found of which 4 included data on patients relevant to the clinical question, these are discussed in the paper. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of the best papers are tabulated. The clinical bottom line is that to date there is no evidence to suggest that measurement of NSE would be beneficial in clinical practice to rule out compression.© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ.
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