• J. Cardiothorac. Vasc. Anesth. · Feb 2011

    The relationship between cerebral oxygen saturation changes and postoperative cognitive dysfunction in elderly patients after coronary artery bypass graft surgery.

    • Emilie de Tournay-Jetté, Gilles Dupuis, Louis Bherer, Alain Deschamps, Raymond Cartier, and André Denault.
    • Department of Psychology, Université du Québec à Montréal, Montreal, Quebec, Canada.
    • J. Cardiothorac. Vasc. Anesth. 2011 Feb 1;25(1):95-104.

    ObjectiveThe aim of this study was to evaluate the predictive value of cerebral regional oxygen saturation (rSO(2)) in the occurrence of postoperative cognitive dysfunction (POCD) in elderly patients undergoing coronary artery bypass graft (CABG) surgery.DesignA prospective study.SettingUniversity hospital.ParticipantsA total of 61 patients (84% male) with a mean age of 70.39 ± 4.69 on a waiting list for CABG surgery were enrolled in the study.InterventionA complete neurocognitive evaluation was performed 1 day before surgery as well as 4 to 7 days and 1 month after surgery. During surgery, rSO(2) was monitored continuously.Measurements And Main ResultsPOCD was defined as a reduction of 1 standard deviation on 2 or more neuropsychologic indices. Forty-six patients (80.7%) developed early POCD, and 23 (38.3%) showed late POCD. Patients whose rSO(2) decreased to less than 50% during the surgery experienced more POCD 4 to 7 days after surgery (p = 0.04). In addition, a decrease of more than 30% from the patient's baseline rSO(2) was associated with POCD 1 month after surgery (p = 0.03).ConclusionIntraoperative cerebral oxygen desaturation is associated with early and late POCD in elderly patients. Cerebral oximetry is a promising tool in the prediction of subtle neuropsychologic deficits and further studies are needed.Crown Copyright © 2011. Published by Elsevier Inc. All rights reserved.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…