• J. Thorac. Cardiovasc. Surg. · Aug 2024

    Robotic-assisted Extended Thymectomy for Large Resectable Thymoma: 21 Years' Experience.

    • Luyu Huang, Zhongmin Li, Feng Li, Hongbin Zhang, Wenqiang Zhang, Aron Elsner, Julia Strauchmann, Marco Nicolas Andreas, Tomasz Dziodzio, Aina Lask, Jens Neudecker, Mahmoud Ismail, Daipeng Xie, Haiyu Zhou, Andreas Meisel, and Jens-C Rueckert.
    • Department of Surgery, Competence Center of Thoracic Surgery, Charité Universitätsmedizin Berlin, Berlin, Germany; Department of Thoracic Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
    • J. Thorac. Cardiovasc. Surg. 2024 Aug 17.

    ObjectiveThis study aims to evaluate the perioperative and midterm oncological outcomes of robotic-assisted thoracic surgery extended thymectomy for patients with large resectable thymomas compared with small thymomas.MethodsThis retrospective single-center study included 204 patients with thymomas who underwent robotic-assisted thoracic surgery extended thymectomy between January 2003 and February 2024. Patients were divided into 2 groups based on the thymoma size (5-cm threshold).ResultsThe study comprised 114 patients (55.9%) in the small thymoma group and 90 patients (44.1%) in the large thymoma group. No significant differences were found between the groups regarding gender, age, proportion of elderly patients, or pathologic high-risk classifications. Apart from a longer operative time (P = .009) in the large thymoma group, no differences were observed between the 2 groups regarding surgical parameters and postoperative outcomes. No deaths occurred within 30 days in either group. During a median follow-up of 61.0 months (95% CI, 48.96-73.04), 4 patients experienced recurrence (1.96%). No significant differences in the 5-year overall survival (P = .25) or recurrence-free survival (P = .43) were observed between groups.ConclusionsRobotic-assisted thoracic surgery extended thymectomy is technically feasible, safe, and effective for treating large resectable thymomas. Moreover, midterm outcomes for patients with completely resected large thymomas were comparable to those with small thymomas during a median follow-up period of up to 5 years.Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.

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